Benefits of Tumeric Research Study

Benefits of Tumeric Research StudyResults of the study revealed that Turmeric was indeed effective.The t-test results show that t Stat is larger, (6.219209872) than t Critical, (2.262157) this is a significant difference and demonstrates we are 95% sure of pain reduction in using Turmeric. (statistical-significance, 2014)Outlining the response to treatment with turmeric, the first seminal typography was published in 1949 in Nature and it discussed the effects of turmeric on the human body and different diseases, turmeric contains curcumin.It has displayed good therapeutic potential against a number of human diseases. The common points coming out of the study revealed good safety, tolerability, and non-toxicity, with doses up to 8 g per day.Poor bioavailability and limited adverse effects inform by some investigators are a major limitation to the therapeutic utility of curcumin. (Subash, Gupta, Sridevi Patchva, Bharat, 2012)Using black stream containing piperine added to curcumi n increases its bioavailability by 2000%, using the same get of curcumin. (turmeric-bioavailability, 2016)Comparing the results to other research, there were six clinical trials consisting of a total of 377 patients, comparing the use of curcumin to placebo in patients with depression.From the Hamilton Rating Scale for Depression, there was a build of 95% confidence interval and significant anti-anxiety effects were reported in 3 of the trials, there were no adverse events reported.There was limited evidence on semipermanent ability and safety of curcumin as the duration of all available studies ranged from 4 to 8 weeks.Curcumin appears to be well-tolerated and safe, it provided the expected results among depressed patients. Planned larger duration controlled trials and larger sample sizes are required with follow-up studies. (Ng , Koh, Chan, Ho, 2017)Curcumin is the main active ingredient of turmeric, it has a yellow colour, the uses are for cooking along with being a salvage for treatment and prevention of inflammatory diseases, it displays strong anti-oxidative and anti-inflammatory activitiesInflammation, be it acute or chronic, plays a major factor in some of the following diseases, obesity progression, type II diabetes, arthritis, pancreatitis, cardiovascular, neurodegenerative and metabolic diseases and certain types of cancer. Turmeric has a long history of use in Ayurvedic medicine for the treatment of inflammatory disorders. (Shehzad, Rehman, Lee, 2012)Dietary supplements for osteoarthritis (OA) and rheumatoid arthritis (RA) require ingredients with antioxidant and anti-inflammatory properties.From a search of 16 clinical studies three supported the use of cats claw used alone or in a combination for osteoarthritis (OA). Two others for rheumatoid arthritis (RA) with omega-3 fatty acids and supported. (Rosenbaum, OMathna, Chavez, Shields, 2010)Anti-inflammatory properties of curcumin for rheumatoid arthritis, turmeric rhizome has been used med icinally in mainland China and India for thousands of years, the active ingredient is curcumin, which is available worldwide. Preclinical studies point to mechanisms of action that are predominantly anti-inflammatory and antineoplastic, (acting to prevent, inhibit or stop the development of a tumour). first human clinical trials demonstrated beneficial effects for dyspepsia, peptic ulcer, inflammatory bowel disease, rheumatoid arthritis, osteoarthritis, uveitis, orbital pseudotumor, ( hump of tissue behind the eye in an sports stadium called the orbit) and pancreatic cancer. Curcumin is well-tolerated the most common side effects are nausea and diarrhoea. (Asher Spelman , 2013)Recent studies confirm curcumins low bioavailability, this has been known for some time, by pairing with black pepper which contains piperine, bioavailability is increased by 2000%. (turmeric-bioavailability, 2016)The significance of turmeric as a treatment approach. In a study titled, A randomized, pilot st udy to assess the efficacy and safety of curcumin patients with rheumatoid arthritis, forty-five patients were selected at random into three groups, group 1 patients receiving curcumin (500 mg), group 2 pickings diclofenac sodium (50mg) and group 3 taking the combination.The primary study endpoints were a reduction in Disease Activity Score (DAS) 28, the secondary endpoints included American College of Rheumatology (ACR) criteria for reduction in tenderness and swelling of joint scores. The researchers found all three treatment groups showed statistically significant changes in their DAS scores, the curcumin only group showed the highest percentage of improvement in overall DAS and ACR scores. More importantly, curcumin treatment was found to be safe and did not relate with any adverse events. (Sayer, 2013)Two possible research issues, one being to run trials with piperine added to the turmeric and measure results with piperine vs without piperine.The second issue would be to see i s what effect the added piperine has on adverse effects.ReferencesAsher, G. N., Spelman , K. (2013, March). pubmed/23594449. Retrieved from ncbi.nlm.nih.gov/https//www.ncbi.nlm.nih.gov/pubmed/23594449Ng , Q. X., Koh, S. S., Chan, H. W., Ho, C. Y. (2017, February 21). pubmed/28236605. Retrieved from ncbi.nlm.nih https//www.ncbi.nlm.nih.gov/pubmed/28236605Rosenbaum, C. C., OMathna, D. P., Chavez, M., Shields, K. (2010, April 2016). 20232616. Retrieved from pubmed https//www.ncbi.nlm.nih.gov/pubmed/20232616Sayer, J. (2013, declination 26). turmeric-extract-found-superior-blockbuster-drug-rheumatoid-arthritis. Retrieved fromhttps//www.greenmedinfo.comShehzad, A., Rehman, G., Lee, Y. S. (2012, December 22). pubmed/23281076. Retrieved from pubmedhttps//www.ncbi.nlm.nih.gov/pubmed/23281076statistical-significance. (2014, April 1). Retrieved from iwh.on.ca https//www.iwh.on.ca/wrmb/statistical-significanceSubash, C., Gupta, Sridevi Patchva, Bharat, B. (2012, November 12). articles/PMC 3535097. Retrieved from ncbi.nlm.nih.gov https//www.ncbi.nlm.nih.gov/pmc/articles/PMC3535097/turmeric-bioavailability. (2016, January 1). Retrieved from dailyhealthpost.com https//dailyhealthpost.com/improve-turmeric-bioavailability/turmericforhealth.com. (2013, September 14). Retrieved from health-benefits-of-black-pepper-and-turmerichttp//www.turmericforhealth.com/turmeric-benefits/health-benefits-of-black-pepper-and-turmeric